ech·o·car·di·o·graph (ěk'ō-kär'dē-ə-grāf') n. An instrument that in a painless and noninvasive manner employs the differential transmission and reflection of ultrasonic waves to image structural and functional abnormalities of the heart. ech'o·car'di·o·graph'ic adj., ech'o·car'di·og'ra·phy (-ŏg'rə-fē) n.