ecocide

[ek-uh-sahyd, ee-kuh-]
noun
the destruction of large areas of the natural environment by such activity as nuclear warfare, overexploitation of resources, or dumping of harmful chemicals.

Origin:
1965–70, Americanism; eco- + -cide

ecocidal, adjective
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World English Dictionary
ecocide (ˈiːkəˌsaɪd, ˈɛkə-)
 
n
total destruction of an area of the natural environment, esp by human agency

Collins English Dictionary - Complete & Unabridged 10th Edition
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Example sentences
Instead, the human race greedily plunges toward ecocide and self-extinction.
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