| 1. | a chronic, irreversible disease of the lungs characterized by abnormal enlargement of air spaces in the lungs accompanied by destruction of the tissue lining the walls of the air spaces. |
| 2. | any abnormal distention of an organ, or part of the body, with air or other gas. |

A chronic disease in which the tiny air sacs in the lungs become stretched and enlarged, so that they are less able to supply oxygen to the blood. Emphysema causes shortness of breath and painful coughing and can increase the likelihood of developing heart disease. Emphysema occurs most frequently in older men who have been heavy smokers.
emphysema em·phy·se·ma (ěm'fĭ-sē'mə, -zē'-)
n.
A pathological condition of the lungs marked by an abnormal increase in the size of the air spaces, resulting in labored breathing and an increased susceptibility to infection. It can be caused by irreversible expansion of the alveoli or by the destruction of alveolar walls. Also called pulmonary emphysema.
An abnormal distention of body tissues caused by retention of air.