Is it farther or further?
1640s, from verb enucleate (1540s), from Latin enucleatus "pure, clean," past participle of enucleare "to lay open, explain in detail," literally "to remove the kernel of" (see ex- + nucleus). Mostly figurative in Latin (the notion is of getting at the "core" of some matter); until mid-19c. advances in science and medicine, usually figurative in English.
enucleate e·nu·cle·ate (ĭ-nōō'klē-āt', ĭ-nyōō'-)
v. e·nu·cle·at·ed, e·nu·cle·at·ing, e·nu·cle·ates
To remove something, such as a tumor or an eye, whole and without rupture from an enveloping cover or sac.
To remove the nucleus of a cell.