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falciparum malaria fal·cip·a·rum malaria (fāl-sĭp'ər-əm, fôl-)
Malaria caused by Plasmodium falciparum and characterized by severe malarial paroxysms that recur about every 48 hours and often by acute cerebral, renal, or gastrointestinal manifestations. Also called malignant tertian malaria.