noun, adjective, verb, -tigued, -ti⋅guing.| 1. | weariness from bodily or mental exertion. |
| 2. | a cause of weariness; slow ordeal; exertion: the fatigue of driving for many hours. |
| 3. | Physiology. temporary diminution of the irritability or functioning of organs, tissues, or cells after excessive exertion or stimulation. |
| 4. | Civil Engineering. the weakening or breakdown of material subjected to stress, esp. a repeated series of stresses. |
| 5. | Also called fatigue duty. Military.
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| 6. | fatigues, Military. fatigue clothes. |
| 7. | of or pertaining to fatigues or any clothing made to resemble them: The guerrilla band wore fatigue pants and field jackets. She brought fatigue shorts to wear on the hike. |
| 8. | to weary with bodily or mental exertion; exhaust the strength of: Endless chatter fatigues me. |
| 9. | Civil Engineering. to subject (a material) to fatigue. |
| 10. | to become fatigued. |
| 11. | Civil Engineering. (of a material) to undergo fatigue. |

fatigue fa·tigue (fə-tēg')
n.
Physical or mental weariness resulting from exertion.
A sensation of boredom and lassitude due to absence of stimulation, to monotony, or to lack of interest in one's surroundings.
The decreased capacity or complete inability of an organism, an organ, or a part to function normally because of excessive stimulation or prolonged exertion.