"You canker blossom!" 3 Shakespearean Insults
1936, from Gen. Emilio Mola's comment at the siege of Madrid during the Spanish Civil War that he would take the city with his four columns of troops outside it and his "fifth column" (quinta columna) in the city.
People willing to cooperate with an aggressor against their own country. The term originated in a remark by Francisco Franco, the Spanish dictator, that he was marching on Madrid with four columns of troops, and that there was a “fifth column” of sympathizers within the city ready to help.