tv. to give someone a very hard time; to abuse someone physically or mentally; to cheat, deceive, or trick someone. (Taboo. Usually objectionable.) : The big guys fucked him over for a while and then let him go.
Dictionary of American Slang and Colloquial Expressions by Richard A. Spears.Fourth Edition. Copyright 2007. Published by McGraw-Hill Education.
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Idioms & Phrases
Treat unfairly, take advantage of, as in This so-called reform is really fucking over the homeless. [Vulgar slang; c. 1960]