Stories We Like: A Guide to the Comma
Old English gamen "game, joy, fun, amusement," common Germanic (cf. Old Frisian game "joy, glee," Old Norse gaman, Old Saxon, Old High German gaman "sport, merriment," Danish gamen, Swedish gamman "merriment"), regarded as identical with Gothic gaman "participation, communion," from Proto-Germanic *ga- collective prefix + *mann "person," giving a sense of "people together."
Meaning "contest played according to rules" is first attested c.1300. Sense of "wild animals caught for sport" is late 13c.; hence fair game (1825), also gamey. Game plan is 1941, from U.S. football; game show first attested 1961.
"lame," 1787, from north Midlands dialect, of unknown origin, perhaps a variant of gammy (tramps' slang) "bad," or from Old North French gambe "leg" (see gambol (n.)).
"brave, spirited," 1725, especially in game-cock "bird for fighting," from game (n.). Middle English had gamesome (adj.) "joyful, playful, sportive."