Medical Dictionary
Main Entry:
graaf·ian follicle Pronunciation:
"gräf-E-&n-, "graf- Function:
noun often capitalized G : a mature follicle in amammalian ovary that contains a liquid-filled cavity and that ruptures during ovulation to release an egg called also
vesicular ovarian follicle de Graaf /d&-'gräf,/ Reinier (1641–1673), Dutch physician and anatomist. De Graaf is regarded as one of the creators of experimental physiology. In 1672 he produced atreatise on the female reproductive organs that is considered one of the seminal works of biology. De Graaf demonstrated ovulation anatomically, pathologically, and experimentally. The treatisecontains the description of the structures now known in English as the graafian follicles. The Swiss anatomist Albrecht von Haller (1708–1777) named them after de Graaf. In 1827 the Germanembryologist Karl Ernst von Baer (1792–1876) discovered that although the graafian follicles contain the eggs from which organisms develop, they are not the eggs themselves.