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1. The top-level entry point web page relating to an individual or institution, or possibly a subject area. This often has a URL consisting of just a hostname, e.g. http://ncsa.uiuc.edu/. All other pages on a website are usually accessible by following links from the home page.
2. The web page a user's web browser is configured to load each time it is started. This will typically default to the home page (sense 1) of the organisation that produced or distributed the browser.