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howell-jolly body

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Medical Dictionary

Main Entry: How·ell–Jol·ly body
Pronunciation: 'hau-&l-zho-'lE-, -'jäl-E-
Function: noun
: one of the basophilic granules thatare prob. nuclear fragments, that sometimes occur in red blood cells, and that indicate by their appearance in circulating blood that red cells are leaving the bone marrow while incompletely mature (asin certain anemias)
Howell, William Henry (1860–1945), American physiologist. Howell was one of the leading physiologists of his time. His early contributions tophysiology concerned the circulatory system, nerve tissue, and the components of blood. His later researches dealt with the coagulation of blood. He described what are now known as Howell-Jolly bodiesin an article published in 1890.
Jolály /zho-lE/, Justin–Marie–Jules (1870–1953), French histologist. Jolly did research on the morphology of bloodand blood-forming tissues and on mammalian embryology. Independently of Howell, he described the Howell-Jolly bodies in a series of articles published 1905–1907.
Merriam-Webster's Medical Dictionary, © 2002 Merriam-Webster, Inc.
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Medical Dictionary

Howell-Jolly body How·ell-Jol·ly body (hou'əl-zhô-lē')
n.
A spherical granule often observed in the stroma of a red blood cell, especially after a splenectomy.

The American Heritage® Stedman's Medical Dictionary
Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
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