[hahy-druh-kawr-tuh-zohn, -sohn]
Biochemistry. a steroid hormone, C 21 H 30 O 5 , of the adrenal cortex, active in carbohydrate and protein metabolism.
Pharmacology. Also called cortisol. a powerful anti-inflammatory drug, C 21 H 30 O 5 , used in the treatment of shock, allergies, certain forms of arthritis, and other conditions.

1950–55; hydro-2 + cortisone

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World English Dictionary
hydrocortisone (ˌhaɪdrəʊˈkɔːtɪˌzəʊn)
Also called: cortisol the principal glucocorticoid secreted by the adrenal cortex; 17-hydroxycorticosterone. The synthesized form is used mainly in treating rheumatic, allergic, and inflammatory disorders. Formula: C21H30O5

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American Heritage
Medical Dictionary

hydrocortisone hy·dro·cor·ti·sone (hī'drə-kôr'tĭ-sōn', -zōn')

  1. A steroid hormone produced by the adrenal cortex that regulates carbohydrate metabolism and maintains blood pressure. Also called cortisol.

  2. A preparation of this hormone obtained from natural sources or produced synthetically and used to treat inflammatory conditions and adrenal failure.

The American Heritage® Stedman's Medical Dictionary
Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
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American Heritage
Science Dictionary
hydrocortisone   (hī'drə-kôr'tĭ-sōn', -zōn')  Pronunciation Key 
A preparation of the hormone cortisol that is obtained naturally or produced synthetically and is used widely in the treatment of inflammatory conditions and allergies.
The American Heritage® Science Dictionary
Copyright © 2002. Published by Houghton Mifflin. All rights reserved.
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Encyclopedia Britannica


an organic compound belonging to the steroid family, the principal hormone secreted by the adrenal glands. It is a potent anti-inflammatory agent and is also used for the palliative treatment of rheumatoid arthritis.

Learn more about hydrocortisone with a free trial on Britannica.com.

Encyclopedia Britannica, 2008. Encyclopedia Britannica Online.
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Example sentences
They do so by reining in a key enzyme involved in inflammation, and they do it
  with more clout than does hydrocortisone.
Once bitten, a mild steroid cream such as hydrocortisone and antihistamine
  tablets can help.
Some patients experienced improvement in symptoms with low-dose hydrocortisone
Try over-the-counter hydrocortisone cream on itchy areas.
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