hyoscyamine

[ hahy-uh-sahy-uh-meen, -min ]

Phonetic (Standard)IPA

noun

, Pharmacology.

a poisonous alkaloid, C 17 H 23 NO 3 , obtained from henbane and other solanaceous plants, used as a sedative, analgesic, mydriatic, and antispasmodic.

hyoscyamine

/ ˌhaɪəˈsaɪəˌmiːn; -mɪn /

a poisonous alkaloid occurring in henbane and related plants: an optically active isomer of atropine, used in medicine in a similar way. Formula: C 17 H 23 NO 3

First recorded in 1855–60; hyoscyam(us) + -ine ²

C19: from New Latin, from Greek huoskuamos (from hus pig + kuamos bean) + amine

In 1832 Robiquet discovered codeine; and in 1833 atropine, aconitine, and hyoscyamine were distinguished by Geiger and Hesse.

Hyoscyamine crystallizes in the acicular form, with greater difficulty even than atropine, it also forms less compact crystals.

I think, therefore, that both Planta and Schmidt must have worked with a mixture of atropine and hyoscyamine.

According to this view hyoscyamine ought to be the hyoscinate of hyoscine, or at any rate an isomer of this body.

Hoehn and Reichardt have recently studied hyoscyamine in a very complete manner.

April 19, 2024tortuous

[tawr-choo-uhs ]

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