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1590s, "pertaining to the hypochondria," also "afflicted with melancholy," from French hypocondriaque (16c.), from Medieval Latin hypochondriacus, from Greek hypokhondriakos "pertaining to the upper abdomen," from hypokhondria (see hypochondria). The noun is from 1630s, "melancholy person;" in the modern sense from 1888.
hypochondriac hy·po·chon·dri·ac (hī'pə-kŏn'drē-āk')
A person afflicted with hypochondria. adj.
Relating to or afflicted with hypochondria.
Relating to or located in the left or right hypochondrium.
A person who constantly believes he or she is ill or about to become ill.