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in efficacy

 - 2 dictionary results
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in⋅ef⋅fi⋅ca⋅cy

  [in-ef-i-kuh-see]
Use in efficacy in a Sentence
–noun
lack of power or capacity to produce the desired effect.
Origin:
1605–15; < LL inefficācia. See in- 3 , efficacy
Dictionary.com Unabridged
Based on the Random House Dictionary, © Random House, Inc. 2009.
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Word Origin & History

inefficacy 
"want of force or virtue to produce the desired effect," 1612, from L.L. inefficacia, from inefficacem (nom. inefficax), from in- "not" + efficax (see efficacy).
Online Etymology Dictionary, © 2001 Douglas Harper
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