Main Entry: insulin resistance Function: noun : reduced sensitivity to insulin by the body's insulin-dependent processes (as glucose uptake, lipolysis, and inhibition ofglucose production by the liver) that results in lowered activity of these processes or an increase in insulin production or both and that is typical of type 2 diabetes but often occurs in the absenceof diabetes
insulin resistancen. A state of diminished effectiveness of insulin in lowering the levels of blood sugar, usually resulting from insulin binding by antibodies, and associated with such conditions as obesity, ketoacidosis, and infection.