Main Entry: in·su·li·tis Pronunciation: "in(t)-s&-'lIt-&s Function: noun : invasion of the pancreatic islets of Langerhans bylymphocytes that produces an inflammatory or autoimmune response and results in destruction of the beta cells of the pancreas
insulitis in·su·li·tis (ĭn'sə-lī'tĭs) n. A histologic change in the islets of Langerhans characterized by edema and the infiltration of small numbers of white blood cells.