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Leydig cells, also known as interstitial cells of Leydig, are found adjacent to the seminiferous tubules in the testicle. They can secrete testosterone and are often closely related to nerves. Leydig cells have round vesicular nuclei and a granular eosinophilic cytoplasm. Nomenclature...
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Male002 Several seminiferous tubules of a testis with stratified germinal epithelium showing the spermatogonia, primary spermatocytes, developing spermatids, Sertoli cells, and the interstitial cells (of Leydig) between the tubules.
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Britannica online encyclopedia article on Leydig cell:...its complex functional interrelationship with FSH is dealt with below in Hormones of the reproductive system. In the male, luteinizing hormone promotes the development of the interstitial tissue (Leydig cells) of the testes and hence promotes the secretion of the male...
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Consulting Staff, University of Tennessee Medical Center Author and Editor Disclosure Synonyms and related keywords: Leydig cell tumor, stromal testis tumor, interstitial testis tumor, interstitial testicular tumor, precocious puberty, androgenizing tumors, feminizing syndrome, virilizing syndrome, testicular...
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The interstitial cells of Leydig which lie in small groups or individually between the seminiferous tubules of the testes, or at the hilum in the ovary, are known to be active in production of androgenic substances, as well as being sensitive to the influence of various trophic hormones.
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Regulatory Cytokine Expression and Interstitial Fluid Formation in the Normal and Inflamed Rat Testis Are Under Leydig Cell Control...
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See: Leydig cells. For related information see also: Cell types.
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Studies of the Interstitial Cells of Leydig. 3. This variety is similar to the preceding, but is characterized by the. presence of large acidophile granules...
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Complex multilocular cystic lesion of rete testis, accompanied by smooth muscle hyperplasia, mimicking intratesticular Leydig cell neoplasm. and (3) extensive stroma with myxoid areas and scattered interstitial Leydig cells. These morphological findings, supported by a wide immunohistochemical panel,
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Glandular changes associated with the spontaneous interstitial cell tumor of the rat testes. In 266 testes of 2-year-old F344 rats, 263 had interstitial cell tumors (ICTs) (98.9%) and 39 had glandular changes (14.7%). These glandular changes were also found in 1 out of 38 1-year-old F344 rat testes (2...
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