isonicotinic acid hydrazide

isonicotinic acid hydrazide

[ahy-suh-nik-uh-tin-ik; hahy-druh-zahyd, -zid]
noun Pharmacology.

Origin:
1950–55; iso- + nicotinic acid; hydraz(ine) + -ide

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Encyclopedia Britannica
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isonicotinic acid hydrazide

drug used in the treatment and prevention of tuberculosis. Isoniazid commonly is used in combination with other drugs, such as rifampin, ethambutol, pyrazinamide, or streptomycin; these drugs are used with isoniazid in order to prevent, or at least delay, the development of isoniazid-resistant strains of tuberculin bacilli. Treatment usually is continued for many months. The most important drug in the therapy of tuberculosis, isoniazid was introduced into medicine in 1952; it usually is administered orally, but it can be given by injection. Side effects may include hepatitis (especially in older patients), peripheral neuropathy, dizziness, and headache.

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Encyclopedia Britannica, 2008. Encyclopedia Britannica Online.
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