Medical Dictionary
Main Entry:
Klebs–Löff·ler bacillus Pronunciation:
'klAps-'lef-l&r-, 'klebz- Function:
noun : a bacterium of the genus
Corynebacterium (
C. diphtheriae) that causes human diphtheria
Löffáler /'l[oe]f-l&r,/ Friedrich August Johannes (1852–1915), Germanbacteriologist. Löffler contributed greatly to the advancement of bacteriology. In 1882 he discovered the bacterium of the genus
Pseudomonas (
P. mallei) that causes glanders. Hediscovered the cause of swine erysipelas and swine plague in 1885. With Paul Frosch (1860–1928) he determined in 1897 that foot-and-mouth disease is caused by a virus. This marked the first timethat the cause of an animal disease was attributed to a virus. They developed a serum against the disease in 1899. The diphtheria bacillus discovered by Klebs in 1883 was isolated in the following yearby Löffler, who also published the first full description of the microorganism which is now known as the Klebs-Löffler bacillus.