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knuckle knuck·le (nŭk'əl)
The prominence of the dorsal aspect of a joint of a finger, especially of one of the joints that connect the fingers to the hand.
A rounded protuberance formed by the bones in a joint.
A kink or loop of intestine, as in a hernia.
To work hard and seriously; stop loafing; buckle down
[1866+; fr the act of putting one's knuckles down to the taw or marble preparing for a careful shot in the game of marbles, a use dating fr the mid-18th century]