lesion

[lee-zhuhn]
noun
1.
an injury; hurt; wound.
2.
Pathology. any localized, abnormal structural change in the body.
3.
Plant Pathology. any localized, defined area of diseased tissue, as a spot, canker, blister, or scab.
verb (used with object)
4.
to cause a lesion or lesions in.

Origin:
1425–75; late Middle English < Middle French < Latin laesiōn- (stem of laesiō) injury, equivalent to Latin laes(us) (past participle of laedere to harm, equivalent to laed- verb stem + -tus past participle suffix, with -dt- > -s-) + -iōn- -ion

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World English Dictionary
lesion (ˈliːʒən)
 
n
1.  any structural change in a bodily part resulting from injury or disease
2.  an injury or wound
 
[C15: via Old French from Late Latin laesiō injury, from Latin laedere to hurt]

Collins English Dictionary - Complete & Unabridged 10th Edition
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Etymonline
Word Origin & History

lesion
1452, from M.Fr. lesion, from L. læsionem (nom. læsio) "injury," from lædere "to strike, hurt, damage," of unknown origin. Originally with ref. to any sort of hurt, whether physical or not.
Online Etymology Dictionary, © 2010 Douglas Harper
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American Heritage
Medical Dictionary

lesion le·sion (lē'zhən)
n.

  1. A wound or an injury.

  2. A localized pathological change in a bodily organ or tissue.

  3. An infected or diseased patch of skin.

The American Heritage® Stedman's Medical Dictionary
Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
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Encyclopedia Britannica
Encyclopedia

lesion

in physiology, a structural or biochemical change in an organ or tissue produced by disease processes or a wound. The alteration may be associated with particular symptoms of a disease, as when a gastric ulcer produces stomach pain, or it may take place without producing symptoms, as in the early stages of cancer. Certain lesions, such as the genital chancre of syphilis, are diagnostic of a particular disease, and early recognition of the physical or biochemical injury can help to prevent later, more serious manifestations of a disease; thus, the recognition and classification of disease lesions is a major part of pathology.

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Encyclopedia Britannica, 2008. Encyclopedia Britannica Online.
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Example sentences
Have any suspicious lesion checked immediately, especially if it has grown
  quickly or is partially flat and partially raised.
Local brain damage of this sort is known to neurologists as a lesion.
It also bears distinctive knife cuts, a pierced ear, and a lesion near the nose.
It makes me wonder what would happen if they tried to lesion at a low pitch.
Image for lesion
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