Medical Dictionary
Main Entry:
Li–Frau·me·ni syndrome Pronunciation:
'lE-frau-'mE-nE- Function:
noun : a rare familial syndrome that is characterizedespecially by a high risk of developing early breast cancer and sarcomas of soft tissue
Li, Frederick P. (b 1940), American epidemiologist. Li held the concurrentpositions of professor of clinical cancer epidemiology at the Harvard School of Public Health and epidemiologist at the National Cancer Institute. His research centered on the identification of personsat high risk of cancer and the genetic and environmental causes of cancer susceptibility.
Fraumeni, Joseph F., Jr. (b 1933), American epidemiologist. Fraumenienjoyed a long association with the National Cancer Institute, eventually becoming director of the institute's Epidemiology and Biostatistics Program. At the same time he served as attending physicianat the Clinical Center of the National Institutes of Health. His research focused on the epidemiology of cancer and the environmental and genetic determinants of the disease.