1–4. tiny, teeny, wee. Little, diminutive, minute, small refer to that which is not large or significant. Little (the opposite of big ) is very general, covering size, extent, number, quantity, amount, duration, or degree: a little boy; a little time. Small (the opposite of large and of great ) can many times be used interchangeably with little, but is especially applied to what is limited or below the average in size: small oranges. Diminutive denotes (usually physical) size that is much less than the average or ordinary; it may suggest delicacy: the baby's diminutive fingers; diminutive in size but autocratic in manner. Minute suggests that which is so tiny it is difficult to discern, or that which implies attentiveness to the smallest details: a minute quantity; a minute exam.