lupus er·y·the·ma·to·sus (ěr'ə-thē'mə-tō'səs, -thěm'ə-) n. Any of several connective tissue disorders, especially systemic lupus erythematosus, that primarily affect women of childbearing age, have a variety of clinical forms, and are characterized by red scaly skin lesions.
[New Latin lupus erythēmatōsus : lupus + erythēmatōsus, erythematous.]