noun, plural maculae [mak-yuh-lee] .
a spot or blotch, especially on one's skin; macule.
an opaque spot on the cornea.
Also called macula lutea, yellow spot. an irregularly oval, yellow-pigmented area on the central retina, containing color-sensitive rods and the central point of sharpest vision.

1350–1400; Middle English < Latin: spot, blemish

macular, adjective
multimacular, adjective Unabridged
Based on the Random House Dictionary, © Random House, Inc. 2014.
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World English Dictionary
macula or macule (ˈmækjʊlə, ˈmækjuːl)
n , pl -ulae, -ules
1.  a small spot or area of distinct colour, esp the macula lutea
2.  any small discoloured spot or blemish on the skin, such as a freckle
[C14: from Latin]
macule or macule (ˈmækjʊlə, ˈmækjuːl, -jʊˌliː)
[C14: from Latin]
'macular or macule

Collins English Dictionary - Complete & Unabridged 10th Edition
2009 © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins
Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009
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Word Origin & History

pl. maculae, from L. macula "spot, stain;" especially the macula lutea in the eye.

1822, from macula.
Online Etymology Dictionary, © 2010 Douglas Harper
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American Heritage
Medical Dictionary

macula mac·u·la (māk'yə-lə)
n. pl. mac·u·las or mac·u·lae (-lē')

  1. Also mac·ule (-yōōl') A spot, stain, or blemish, especially an area of discoloration on the skin caused by excess or lack of pigment.

  2. A small area distinguishable from the surrounding tissue.

  3. The macula lutea.

mac'u·lar adj.
The American Heritage® Stedman's Medical Dictionary
Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
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American Heritage
Science Dictionary
macula   (māk'yə-lə)  Pronunciation Key 
Plural maculae (māk'yə-lē') or maculas
  1. A minute yellowish area located near the center of the retina of the eye, at which visual perception is most acute.

  2. A discolored spot on the skin that is not elevated above the surface.

The American Heritage® Science Dictionary
Copyright © 2002. Published by Houghton Mifflin. All rights reserved.
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Example sentences
One has age-related macular degeneration, the main cause of blindness in rich
So my family tends to get cataracts, glaucoma and macular degeneration.
It is squirted into the eyeballs of people with macular degeneration as a
  treatment for the blindness-causing disease.
Macular degeneration is an eye disorder that slowly destroys sharp, central
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