| 1. | a fashionable residential district west of Philadelphia. |
| 2. | any fashionable district where socially prominent people live. |
verb, -lined, -lin⋅ing, adjective | 1. | to inject a narcotic, esp. heroin, directly into a vein. |
| 2. | to use or enjoy something without restriction: to mainline on TV movies. |
| 3. | to inject (a narcotic, esp. heroin) directly into a vein. |
| 4. | to use, enjoy, or imbibe (something) without restriction: mainlining coffee all day long. |
| 5. | having a principal, established, or widely accepted position; major; mainstream: the membership of mainline churches. |