a shackle for the hand; handcuff.
Usually, manacles. restraints; checks.
verb (used with object), manacled, manacling.
to handcuff; fetter.
to hamper; restrain: He was manacled by his inhibitions.

1275–1325; Middle English, variant of manicle < Middle French: handcuff < Latin manicula small hand, handle of a plow. See manus, -i-, -cle1

unmanacled, adjective Unabridged
Based on the Random House Dictionary, © Random House, Inc. 2014.
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World English Dictionary
manacle (ˈmænəkəl)
1.  (usually plural) a shackle, handcuff, or fetter, used to secure the hands of a prisoner, convict, etc
2.  to put manacles on
3.  to confine or constrain
[C14: via Old French from Latin manicula, diminutive of manus hand]

Collins English Dictionary - Complete & Unabridged 10th Edition
2009 © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins
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Word Origin & History

mid-14c., "a fetter for the hand," from O.Fr. manicle, from L. manicula "handle," lit. "little hand," dim. of manicæ "long sleeves of a tunic, manacles," from manus "hand" (see manual). The verb is attested from c.1300. Related: Manacled; manacles.
Online Etymology Dictionary, © 2010 Douglas Harper
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Example sentences
Two nicely plump, pink-cheeked maidens are arranged on the grey rocks behind
  the actor, manacled and in chains.
For the first time since the trial began, he was brought into court manacled.
Manacled and cramped into ghastly holds, many of the captives did not survive
  the voyage.
And, without a sustained effort to hone this skill you'll remain solidly
  manacled to the fray.
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