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Meleney's gangrene Me·le·ney's gangrene (mə-lē'nēz)
A form of gangrene of the skin and subcutaneous tissues, usually following an operation, caused by a synergistic interaction between microaerophilic nonhemolytic streptococci and aerobic hemolytic staphylococci; it produces extensive tissue necrosis with ulceration. Also called Meleney's ulcer.