metachromatic leukodystrophy

Medical Dictionary

metachromatic leukodystrophy n.
An inherited metabolic disorder characterized by myelin loss, accumulation of metachromatic lipids in the white matter of the central and peripheral nervous systems, a marked excess of sulfatidates in white matter and in urine, progressive paralysis, and dementia.

The American Heritage® Stedman's Medical Dictionary
Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
Cite This Source
Encyclopedia Britannica
Encyclopedia

metachromatic leukodystrophy

rare inherited metabolic disease in which the lack of a key enzyme causes loss of the protective myelin sheath from the white matter of the brain, resulting in psychological disturbances, mental deterioration, and sensory and motor defects.

Learn more about metachromatic leukodystrophy with a free trial on Britannica.com.

Encyclopedia Britannica, 2008. Encyclopedia Britannica Online.
Cite This Source
Copyright © 2014 Dictionary.com, LLC. All rights reserved.
  • Please Login or Sign Up to use the Recent Searches feature