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or (especially British) metastasise

[muh-tas-tuh-sahyz] /məˈtæs təˌsaɪz/
verb (used without object), metastasized, metastasizing.
Pathology. (of malignant cells or disease-producing organisms) to spread to other parts of the body by way of the blood or lymphatic vessels or membranous surfaces.
to spread injuriously:
Street gangs have metastasized in our city.
to transform, especially into a dangerous form:
The KGB metastasized after the fall of the Soviet Union. Truth metastasized into lurid fantasy.
Origin of metastasize
1905-10; metastas(is) + -ize Unabridged
Based on the Random House Dictionary, © Random House, Inc. 2015.
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British Dictionary definitions for metastasize


verb (intransitive)
(pathol) (esp of cancer cells) to spread to a new site in the body via blood or lymph vessels
(of a problem) to deteriorate or spread into new areas
Collins English Dictionary - Complete & Unabridged 2012 Digital Edition
© William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins
Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012
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Word Origin and History for metastasize

1826, from metastasis + -ize. Related: Metastasized; metastasizing.

Online Etymology Dictionary, © 2010 Douglas Harper
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metastasize in Medicine

metastasize me·tas·ta·size (mə-tās'tə-sīz')
v. me·tas·ta·sized, me·tas·ta·siz·ing, me·tas·ta·siz·es
To be transmitted or transferred by or as if by metastasis.

The American Heritage® Stedman's Medical Dictionary
Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
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metastasize in Science
A cancerous tumor formed by transmission of malignant cells from a primary cancer located elsewhere in the body.

metastasize verb
The American Heritage® Science Dictionary
Copyright © 2002. Published by Houghton Mifflin. All rights reserved.
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