verb (used without object), metastasized, metastasizing.
Pathology. (of malignant cells or disease-producing organisms) to spread to other parts of the body by way of the blood or lymphatic vessels or membranous surfaces.
to spread injuriously: Street gangs have metastasized in our city.
to transform, especially into a dangerous form: The KGB metastasized after the fall of the Soviet Union. Truth metastasized into lurid fantasy.
Also, especially British, metastasise.

1905–10; metastas(is) + -ize Unabridged
Based on the Random House Dictionary, © Random House, Inc. 2014.
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World English Dictionary
metastasize or metastasise (mɪˈtæstəˌsaɪz)
1.  pathol (esp of cancer cells) to spread to a new site in the body via blood or lymph vessels
2.  (of a problem) to deteriorate or spread into new areas
metastasise or metastasise

Collins English Dictionary - Complete & Unabridged 10th Edition
2009 © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins
Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009
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Word Origin & History

formed 1907 from metastasis. Related: Metastasized.
Online Etymology Dictionary, © 2010 Douglas Harper
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American Heritage
Medical Dictionary

metastasize me·tas·ta·size (mə-tās'tə-sīz')
v. me·tas·ta·sized, me·tas·ta·siz·ing, me·tas·ta·siz·es
To be transmitted or transferred by or as if by metastasis.

The American Heritage® Stedman's Medical Dictionary
Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
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American Heritage
Science Dictionary
metastasis   (mə-tās'tə-sĭs)  Pronunciation Key 
A cancerous tumor formed by transmission of malignant cells from a primary cancer located elsewhere in the body.

metastasize verb
The American Heritage® Science Dictionary
Copyright © 2002. Published by Houghton Mifflin. All rights reserved.
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Example sentences
Take a virtual tour into the growth of a tumor and watch how blood vessels help
  tumors grow and metastasize.
Some are fast moving and aggressive, others are never fated to metastasize.
Other protein signatures may hint at a more advanced tumor that is poised to
Most neoplasms seen in the head and neck region are locally invasive tumors,
  which can metastasize to local lymph nodes.
Related Words
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