Being a Catholic helps in some midwestern states, but less so in the heavily Protestant communities of South Carolina.
Humor, blue eyes, and midwestern politeness: what more could the ladies (and a good portion of the men) of New York want?
Simon is 51 years old, tall, and possessed of a big smile that conveys midwestern values and steadiness.
1926, in U.S. geographical sense, from earlier Midwestern (1889) in reference to a group of states originally listed as W.Virginia, Kentucky, Tennessee, Missouri, Kansas, and Arkansas; now generally meaning states somewhat further northwest. Related: Midwesterner.