mis·trust (mĭs-trŭst') n. Lack of trust or confidence arising from suspicion. See Synonyms at uncertainty. v. mis·trust·ed, mis·trust·ing, mis·trusts v. tr. To regard without trust or confidence. v. intr. To be wary, suspicious, or doubtful. mis·trust'ful adj., mis·trust'ful·ly adv., mis·trust'ful·ness n. |