monoclonal antibody
monoclonal antibody
1970–75
Based on the Random House Dictionary, © Random House, Inc. 2012.
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| the offspring of a zebra and a donkey. |
| an arrangement of five objects, as trees, in a square or rectangle, one at each corner and one in the middle. |
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monoclonal antibody n.
Any of a class of highly specific antibodies produced by the clones of a single hybrid cell formed in the laboratory by the fusion of a B cell with a tumor cell and widely used in medical and biological research.
Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
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monoclonal antibody
antibody produced artificially by a genetic engineering technique. Production of monoclonal antibodies was one of the most important techniques of biotechnology to emerge during the last quarter of the 20th century. When activated by an antigen, a circulating B cell multiplies to form a clone of plasma cells, each secreting identical immunoglobulin molecules. It is such immunoglobulins-derived from the descendants of a single B cell-that are called monoclonal antibodies.
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