multiple myeloma

noun Pathology.
a malignant plasma cell tumor of the bone marrow that destroys bone tissue.

Origin:
1895–1900; myel- + -oma

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Based on the Random House Dictionary, © Random House, Inc. 2014.
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American Heritage
Medical Dictionary

multiple myeloma n.
A malignant proliferation of plasma cells in bone marrow causing numerous tumors and characterized by the presence of abnormal proteins in the blood.

The American Heritage® Stedman's Medical Dictionary
Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
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Example sentences
But ironically, thalidomide has recently seen resurgence on a limited scale as
  a therapy for multiple myeloma, a deadly disease.
In multiple myeloma, plasma cells grow out of control in the bone marrow and
  form tumors in the areas of solid bone.
He valiantly fought multiple myeloma for more than five years.
Multiple myeloma often affects or involves the bone, but is not considered a
  bone tumor.
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