noun Pathology.
a condition characterized by thickening of the skin, blunting of the senses and intellect, and labored speech, associated with hypothyroidism.
Also, myxoedema.

1875–80; myx- + edema

myxedematous [mik-si-dem-uh-tuhs, -dee-muh-] , adjective
myxedemic [mik-si-dem-ik] , adjective
postmyxedematous, adjective
postmyxedemic, adjective Unabridged
Based on the Random House Dictionary, © Random House, Inc. 2014.
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World English Dictionary
myxoedema or myxedema (ˌmɪksɪˈdiːmə)
See also cretinism a disease resulting from underactivity of the thyroid gland characterized by puffy eyes, face, and hands and mental sluggishness
myxedema or myxedema
myxoedemic or myxedema
myxoedematous or myxedema
myxe'demic or myxedema
myxe'dematous or myxedema

Collins English Dictionary - Complete & Unabridged 10th Edition
2009 © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins
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American Heritage
Medical Dictionary

myxedema myx·e·de·ma (mĭk'sĭ-dē'mə)
A disease caused by decreased activity of the thyroid gland in adults and characterized by dry skin, swellings around the lips and nose, mental deterioration, and a subnormal basal metabolic rate.

myx'e·dem'a·tous (-děm'ə-təs, -dē'mə-) or myx'e·dem'ic (-děm'ĭk) adj.
The American Heritage® Stedman's Medical Dictionary
Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
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Example sentences
Myxedema coma is a rare, life-threatening complication of untreated hypothyroidism.
Myxedema coma is treated with intravenous thyroid replacement and steroid medications.
Both thyroid storm and myxedema coma have high mortality rates even with therapy.
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