negate

[ni-geyt, neg-eyt]
verb (used with object), negated, negating.
1.
to deny the existence, evidence, or truth of: an investigation tending to negate any supernatural influences.
2.
to nullify or cause to be ineffective: Progress on the study has been negated by the lack of funds.
verb (used without object), negated, negating.
3.
to be negative; bring or cause negative results: a pessimism that always negates.

Origin:
1615–25; < Latin negātus (past participle of negāre to deny, refuse), equivalent to neg- (variant of nec not; see neglect) + -ā- theme vowel + -tus past participle suffix

negator, negater, noun
renegate, verb (used with object), renegated, renegating.
self-negating, adjective
unnegated, adjective
Dictionary.com Unabridged
Based on the Random House Dictionary, © Random House, Inc. 2014.
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World English Dictionary
negate (nɪˈɡeɪt)
 
vb
1.  to make ineffective or void; nullify; invalidate
2.  to deny or contradict
 
[C17: from Latin negāre, from neg-, variant of nec not + aio I say]
 
ne'gator
 
n
 
ne'gater
 
n

Collins English Dictionary - Complete & Unabridged 10th Edition
2009 © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins
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Etymonline
Word Origin & History

negate
1837, back formation from negation. Related: Negated; negates; negating.
Online Etymology Dictionary, © 2010 Douglas Harper
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Example sentences
There are road blocks in their path that negate some of the advantages of youth.
Driving around the world as opposed to flying is meant to negate jet lag and
  culture shock.
Ignoring this will negate the gains this country and its people have achieved.
You negate your entire premise with your first paragraph.
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