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nephrotic syndrome ne·phrot·ic syndrome (nə-frŏt'ĭk)
A clinical state marked by edema, albuminuria, decreased plasma albumin, doubly refractile bodies in the urine, and usually increased blood cholesterol. It results from increased permeability of the glomerular capillary basement membranes. Also called nephrosis.
group of signs of kidney malfunction, including a low level of albumin (a protein) and a high level of lipids (fats) in the blood, proteins in the urine, and the accumulation of fluid in the tissues. Nephrotic syndrome typically results in the loss of more than 3.5 grams of proteins per day. It may result from streptococcal infection, lupus erythematosus, renal vein thrombosis, or heavy-metal poisoning.