number one

oneself, especially one's own well-being or interests: to look out for number one.
a person, company, etc., that is first in rank, order, or prestige: Our team is number one.
of the highest in quality, status, importance, etc.; first-rate: a number one performance.
first in rank, order, or prestige: the number one book on the bestseller list.
urination: used especially by or with reference to children.
make/do/go number one, Informal. to urinate: used especially by or with reference to children.

1830–40 Unabridged
Based on the Random House Dictionary, © Random House, Inc. 2014.
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World English Dictionary
number one
1.  the first in a series or sequence
2.  oneself an informal phrase for myself : to look after number one
3.  informal the most important person; leader, chief: he's number one in the organization
4.  informal the bestselling pop record in any one week
5.  euphemistic the act or an instance of urination
6.  a haircut in which the hair is cut very close to the head with an electric shaver
7.  first in importance, urgency, quality, etc: number one priority
8.  informal (of a pop record) having reached the top of the charts

Collins English Dictionary - Complete & Unabridged 10th Edition
2009 © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins
Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009
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Example sentences
The only thing they know is who's number one and who's number two.
Concrete, the number one construction material, is a major source of
  climate-warming gases.
That's why vaccines are the foundation's number one priority.
At many universities, research is the number one criteria for tenure.
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