OdfendOd*fend"\, v. i. 1. To transgress the moral or divine law; to commit a crime; to stumble; to sin. Whosoever shall keep the whole law, and yet offend in one point, he is guilty of all. --James ii. 10. If it be a sin to cevet honor, I am the most offending soul alive. --Shak. 2. To cause dislike, anger, or vexation; to displease. I shall offend, either to detain or give it. --Shak. To offend against, to do an injury or wrong to; to commit an offense against. "We have offended against the Lord already." --2 Chron. xxviii. 13.