It is thought to be only by impressing these images upon the imagination, that he can operate upon our souls.
But in what way did that operate upon his exertions as a writer?
He now began to operate upon his friend; and he achieved a brilliant success.
Where it does not, it never can have any title to operate upon us.
Three of these knobs are furnished with points, which form an instrument well fitted to operate upon a hard thick skin.
The doors were made of plank, and he could not get at the hinges to operate upon them.
It was only in 1808 that he was in a position to operate upon a larger scale.
How did it operate upon the consumption of beer, of spirits?
But he requires patients to operate upon; and the photographer, with whom he is acquainted, recommended him to apply to me.
It is best to begin to operate upon the skin half an hour after it has been flayed.
c.1600, "to be in effect," back-formation from operation, or else from Latin operatus, past participle of operari "to work, labor, toil, take pains" (in Late Latin "to have effect, be active, cause"). Surgical sense is first attested 1799. Meaning "to work machinery" is from 1864 in American English. Related: Operated; operating. Operating system in the computer sense is from 1961.
operate op·er·ate (ŏp'ə-rāt')
v. op·er·at·ed, op·er·at·ing, op·er·ates
To perform surgery.