It operated a fleet of very old airplanes and had such a woeful safety record that FAA inspectors wanted to ground it.
And he has said he became "uncomfortable" when he learned that the surgeon who operated on his liver was Muslim.
Some more recent examples: Intel was founded in 1968 and operated in a highly competitive, capital intensive industry.
c.1600, "to be in effect," back-formation from operation, or else from Latin operatus, past participle of operari "to work, labor, toil, take pains" (in Late Latin "to have effect, be active, cause"). Surgical sense is first attested 1799. Meaning "to work machinery" is from 1864 in American English. Related: Operated; operating. Operating system in the computer sense is from 1961.
operate op·er·ate (ŏp'ə-rāt')
v. op·er·at·ed, op·er·at·ing, op·er·ates
To perform surgery.