Word Origin & History
constellation (representing Aesculapius), 1658, from L., from Gk. ophioukhos, lit. "holding a serpent," from ophis "serpent" + stem of ekhein "to hold, have, keep." The constellation is equatorial, and Milton's "Ophiuchus huge in th' Arctick Sky" ("Paradise Lost") is a rare lapse for a poet who generally
knew his astronomy.