osteogenesis imperfecta

osteogenesis imperfecta

noun Pathology.
a rare hereditary disease in which abnormal connective tissue development leads to fragile bones subject to fracture.

1900–05; < Neo-Latin: imperfect osteogenesis

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World English Dictionary
osteogenesis imperfecta (ˌɪmpəˈfɛktə)
Also called: brittle bone syndrome a hereditary disease caused by a collagen abnormality, causing fragility of the skeleton which results in fractures and deformities

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American Heritage
Medical Dictionary

osteogenesis imperfecta osteogenesis im·per·fec·ta (ĭm'pər-fěk'tə)
A hereditary disease marked by abnormal fragility and plasticity of bone, with recurring fractures resulting from minimal trauma, deformity of long bones, a bluish coloration of the sclerae, and often the development of otosclerosis. Also called brittle bones.

The American Heritage® Stedman's Medical Dictionary
Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
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American Heritage
Science Dictionary
osteogenesis imperfecta   (ŏs'tē-ə-jěn'ĭ-sĭs ĭm'pər-fěk'tə)  Pronunciation Key 
A hereditary disease characterized by abnormally brittle, easily fractured bones.
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Copyright © 2002. Published by Houghton Mifflin. All rights reserved.
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