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pickwickian syndrome pick·wick·i·an syndrome (pĭk-wĭk'ē-ən)
A syndrome characterized by extreme obesity, hypoventilation, and general debility.
a complex of respiratory and circulatory symptoms associated with extreme obesity. The name originates from the fat boy depicted in Charles Dickens's The Pickwick Papers, who showed some of the same traits. (By some definitions, to be obese is to exceed one's ideal weight by 20 percent or more; an extremely obese person would exceed the optimum weight by a much larger percentage.) This condition often occurs in association with sleep apnea, which is another common complication of obesity.