point of no return

noun
1.
Aviation. the point in a flight at which an aircraft will lack sufficient fuel to return to its starting point.
2.
the critical point in an undertaking, decision-making process, etc., where one has committed oneself irrevocably to a course of action or policy.

Origin:
1940–45

Dictionary.com Unabridged
Based on the Random House Dictionary, © Random House, Inc. 2013.
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Collins
World English Dictionary
point of no return
 
n
1.  a point at which an irreversible commitment must be made to an action, progression, etc
2.  a point in a journey at which, if one continues, supplies will be insufficient for a return to the starting place

Collins English Dictionary - Complete & Unabridged 10th Edition
2009 © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins
Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009
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00:10
Point of no return is always a great word to know.
So is callithumpian. Does it mean:
the offspring of a zebra and a donkey.
a children's mummer's parade, as on the Fourth of July, with prizes for the best costumes.
American Heritage
Idioms & Phrases

point of no return

The place in a course of action beyond which reversal is not possible. For example, Once the contract is signed, we've reached the point of no return. This expression comes from aviation, where it signifies the point where an aircraft does not have enough fuel to return to the starting point. [c. 1940]

The American Heritage® Dictionary of Idioms by Christine Ammer.
Copyright © 1997. Published by Houghton Mifflin.
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Example sentences
But she knew the economy was at the point of no return.
The fact is, there is a point of no return with some customers, some of whom
  you really can't do business with.
But it's time for a deep reflection, once arrived at the point of no return.
The sphere represents the event horizon, or the point of no return.
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