| a change in a single base in a nucleotide sequence. |

| point mutation n. A mutation that changes only one small area or one nucleotide in a gene. |
point mutation n.
A mutation that involves a single nucleotide and may consist of loss of a nucleotide, substitution of one nucleotide for another, or the insertion of an additional nucleotide.
| point mutation
A mutation in which one nucleotide is added, deleted, or replaced by another. Point mutations include missense, nonsense, frameshift, and silent mutations. |