point mutation

noun Genetics.
a change in a single base in a nucleotide sequence.

Origin:
1920–25

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American Heritage
Medical Dictionary

point mutation n.
A mutation that involves a single nucleotide and may consist of loss of a nucleotide, substitution of one nucleotide for another, or the insertion of an additional nucleotide.

The American Heritage® Stedman's Medical Dictionary
Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
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American Heritage
Science Dictionary
point mutation  
A mutation in which one nucleotide is added, deleted, or replaced by another. Point mutations include missense, nonsense, frameshift, and silent mutations.
The American Heritage® Science Dictionary
Copyright © 2002. Published by Houghton Mifflin. All rights reserved.
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Example sentences
In a point mutation, a single letter of the genetic code changes to another letter.
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