point of no return

noun
1.
Aviation. the point in a flight at which an aircraft will lack sufficient fuel to return to its starting point.
2.
the critical point in an undertaking, decision-making process, etc., where one has committed oneself irrevocably to a course of action or policy.

Origin:
1940–45

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Based on the Random House Dictionary, © Random House, Inc. 2014.
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World English Dictionary
point of no return
 
n
1.  a point at which an irreversible commitment must be made to an action, progression, etc
2.  a point in a journey at which, if one continues, supplies will be insufficient for a return to the starting place

Collins English Dictionary - Complete & Unabridged 10th Edition
2009 © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins
Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009
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American Heritage
Idioms & Phrases

point of no return

The place in a course of action beyond which reversal is not possible. For example, Once the contract is signed, we've reached the point of no return. This expression comes from aviation, where it signifies the point where an aircraft does not have enough fuel to return to the starting point. [c. 1940]

The American Heritage® Dictionary of Idioms by Christine Ammer.
Copyright © 1997. Published by Houghton Mifflin.
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Example sentences
Various stakeholders will squabble and object until financial conditions
  deteriorate past the point of no return.
The planet is already heating up, and the point of no return may be only
  decades away.
He felt that his team had already altered the blood flow of the brain beyond
  the point of no return.
We were able to take the process far enough to the point of no return, so that
  no one could turn back the clock.
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