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prausnitz-küstner reaction

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Medical Dictionary

Main Entry: Praus·nitz–Küst·ner reaction
Pronunciation: 'praus-nits-'k[ue]st-n&r-
Function: noun
: PASSIVE TRANSFER
Prausnitz, Carl Willy (1876–1963), German bacteriologist. Prausnitz'scareer began with a series of positions at various institutes of hygiene and public health throughout Germany. His research centered on cholera, hay fever, general epidemiology, and the standardizationof sera. Several of his publications dealt with hay fever toxins and antitoxins. In 1921 he demonstrated the transferability of local hypersensitivity by the intradermal injection of serum of anallergic person into a normal person.
Küstner, Heinz (1897–1963), German gynecologist. After holding positions at several medical clinics for women in Germany,Küstner went on to become a professor of obstetrics and gynecology and chief physician at a hospital in Leipzig. His areas of research included endocrinology, pregnancy, puerperal fever, andgynecology. In 1930 he published a study of job-related injuries to the reproductive system incurred by working women.
Merriam-Webster's Medical Dictionary, © 2002 Merriam-Webster, Inc.
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Medical Dictionary

Prausnitz-Küstner reaction Praus·nitz-Küst·ner reaction (prous'nĭts-küst'nər)
n.
A reaction based on passive transfer of allergic sensitivity in which serum from an allergic individual is injected into cutaneous sites on a normal individual and the injected sites are then exposed to antigens to which the donor is allergic; the cutaneous sites show a characteristic wheal-and-flare reaction.

The American Heritage® Stedman's Medical Dictionary
Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
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